Dry granulator granulation technology is a new technology in recent years at home and abroad, the pharmaceutical industry and application in the field of development is very rapid. With the further promotion and application of dry granulator industry in the pharmaceutical industry, the related technology and equipment market demand is also showing a trend of expansion.
At present a lot of domestic dry granulating machine manufacturers, domestic equipment can basically meet the needs of the domestic market. But due to the associated enterprises lack of R & D and innovation investment, domestic equipment has poor stability, high failure rate, the main problems are: bad, water leakage, roll roll misalignment, producing a large quantity of dust, low yield, difficult to clean, pressure is not stable and so on the question.
Dry granulator efficacy
The production efficiency is low: because of poor shape, the equipment power low, dry granulator production efficiency is much lower than the steam granulation.
Equipment: because unprofitable, less dry granulator is often a lack of equipment, such as condensers, grading sieve, transmitting system, affect the efficiency of production and processing.
Equipment: hard extrusion leads to poor durability wear serious, consumable costs increase, use fixed number of year decrease.
Concerned expert points out, dry granulator granulation technology is a new technology in recent years, which has the advantages of adding materials in traditional Chinese medicine extract powder, can be directly granulation, without wet, mixing, drying and other processes, process is simple, can effectively ensure the quality of traditional Chinese medicine. With the continuous expansion of domestic pharmaceutical industry, especially the traditional Chinese medicine industrialization advancement, dry granulating machine technology and equipment will be further extended. The relevant domestic production enterprises should try to strengthen the technical research and development, improve the domestic equipment problems, to better meet the needs of the market.
Dry granulating machine is mainly composed of a conveying system, reversing conveying system, extrusion system, crushing system, front cover system, cooling system, whole grain system, hydraulic system, body, cover a few parts plate, rotary screen system, working in the state of complete seal, and all contact with the material components easy disassembly and cleaning, effectively prevent dust leakage, reducing the possibility of contamination, reduce the cleaning area, more in line with the requirement of pharmaceutical production GMP.
Dry granulating machine clean, saving drying environment, reduce pollution emissions, is one of the widely used pharmaceutical technology is very promising.
Stem defects granulator granulation effect mainly in the following aspects:
Particles forming poor: no steam conditioning and starch, granule forming dry granulator is low, high rate of powder. Some special stages, such as high-grade feed and pig pellets, add a high content of sugar, difficult to be formed; the powder material, it is difficult to molding. Need to add extra water to assist, serious impact on grain quality.
Pelleting Temperature High: due to molding difficult, so the granulation speed, friction generating more heat, doing teaching slot and porket granular material, high temperature has a destructive effect on active ingredients.
Grain hardness: the grain moisture content of dry granulator in 10% ~ 12%, through hard extrusion in the granule hardness than steam granulation, the palatability of feed intake of pigs and the negative effect.
Particulate water solubility difference: hard extrusion has high hardness, also let the particles are difficult to dissolve in water, influence the particle feed digestion. |
