Dry granulating machine clean, saving drying environment, reduce pollution emissions, is one of the widely used pharmaceutical technology is very promising. Dry granulating machine technology, innovation is a strategy of granulation technology, this model realizes the dealer and the approval of granular material pig farms into grain processing plant, save many intermediate links, reduce a lot of intermediate cost. For example: transportation costs, marketing costs, processing costs, enhance the competitiveness of terminal itself. Dry granulator granulation technology is a new technology in recent years, dry granulating machine has the advantages of adding materials in traditional Chinese medicine extract powder, can be directly granulation, without wet, mixing, drying and other processes, process is simple, can effectively ensure the quality of traditional Chinese medicine. With the continuous expansion of domestic pharmaceutical industry, especially the traditional Chinese medicine industrialization advancement, dry granulating machine technology and equipment will be further extended. The relevant domestic production enterprises should try to strengthen the technical research and development, improve the domestic equipment problems, to better meet the needs of the market. Dry granulation technology by roller press granulating machine. With traditional Chinese medicine the relative density of extract, the spray drying to obtain dry extract powder, add some accessories, to squeeze dry granulating machine pressed into thin slices, and then crushed into particles. The method needs less materials, is helpful to improve the stability of the particles, disintegration and soluble powder. General dry extract powder and supplementary material 0.5-1 times. Should pay attention to but also, by spray drying of the dry extract hygroscopicity strong. Therefore, application of key application of this method is to find suitable accessories, accessories should be adhered to some extent, also not easy absorption of moisture, such as lactose, mannitol, pregelatinized starch, water-soluble acrylic resin and cellulose derivatives, etc..
Dry granulating machine is mainly composed of a conveying system, reversing conveying system, extrusion system, crushing system, front cover system, cooling system, whole grain system, hydraulic system, body, cover a few parts plate, rotary screen system, in a completely sealed state of the work, and all contact with the material components easy disassembly and cleaning, effectively prevent dust leakage, reducing the possibility of contamination, reduce the cleaning area, more in line with the requirement of pharmaceutical production GMP.
The dry granulating machine manufacturers, domestic equipment can basically meet the needs of the domestic market. But due to the associated enterprises lack of R & D and innovation investment, domestic equipment has poor stability, high failure rate, the main problems are: bad, water leakage, roll roll misalignment, producing a large quantity of dust, low yield, difficult to clean, pressure is not stable and so on the question. |
