Dry granulating machine is the second generation of granulation method "one step granulating" developed a new method for granulating, pelleting process is a environmental protection type, a step in this process is to boiling granulating spray technology and integrated use of technology, dry granulating machine makes the traditional mixing, granulation, the drying process of a finished in the same sealed container. Similarly, adhesive, its equipment and process a great deal, after cleaning for sewage treatment, and granulating time is too long. The new equipment powder pressed into a pellet. Dry granulating machine technology by roller press granulating machine. With traditional Chinese medicine the relative density of extract, the spray drying to obtain dry extract powder, add some accessories, to squeeze dry granulating machine pressed into thin slices, and then crushed into particles. The method needs less materials, is helpful to improve the stability of the particles, disintegration and soluble powder. General dry extract powder and supplementary material 0.5-1 times. Should pay attention to but also, by spray drying of the dry extract hygroscopicity strong. Therefore, application of key application of this method is to find suitable accessories, accessories should be adhered to some extent, also not easy absorption of moisture, such as lactose, mannitol, pregelatinized starch, water-soluble acrylic resin and cellulose derivatives, etc.. The pharmaceutical industry involved in the various activities of pharmaceutical raw materials and processing one or more excipients, these raw materials are mostly fine powder, and the powder particle size is not a, uneven density, not good fluidity, easy molding. Therefore, must be a key granulation process, can be carried out under the tablet, capsule filling or raw materials directly packaging in the form of particles.
Dry granulating machine has the advantages of simple process, particles out can directly use, does not require drying, save manpower, can greatly improve the work efficiency, the production process of low temperature rise, very suitable for heat sensitive materials. Intermediate improves the quality of the product made of uniform particles, pine is suitable, the particle size distribution is narrow, round shape, good fluidity, particles can be prepared by the small color difference, the required particle. |
